1. What is mg/kg to mg/m² Conversion?

The mg/kg to mg/m² conversion is used in pharmacology to adjust medication doses based on body surface area (BSA) rather than just body weight. This provides a more accurate dosing method, especially for chemotherapy and other potent medications.

2. How Does the Calculator Work?

The calculator uses the following formula:

Where:

• \( \text{Dose (mg/kg)} \) — Original dose per kilogram of body weight
• \( \text{Weight (kg)} \) — Patient's weight in kilograms
• \( \text{BSA (m²)} \) — Patient's body surface area in square meters
• \( \text{Percentage Adjustment} \) — Clinical adjustment factor (100% = no adjustment)

Explanation: The formula converts weight-based dosing to surface area-based dosing, with an optional percentage adjustment for clinical factors.

3. Importance of Dose Conversion

Details: Body surface area correlates better with metabolic rate and drug clearance than body weight alone, making it particularly important for drugs with narrow therapeutic windows.

4. Using the Calculator

Tips: Enter the original dose in mg/kg, patient's weight in kg, BSA in m², and any percentage adjustment (default is 100%). All values must be positive numbers.

5. Frequently Asked Questions (FAQ)

Q1: When should I use mg/m² dosing?
A: Most commonly used for chemotherapy, pediatric dosing, and drugs where toxicity correlates with BSA.

Q2: How do I calculate BSA?
A: BSA can be calculated using formulas like DuBois or Mosteller, or measured directly in clinical settings.

Q3: What does the percentage adjustment mean?
A: This allows clinicians to adjust the dose based on individual patient factors (e.g., renal function, age, comorbidities).

Q4: Are there limitations to this conversion?
A: Some drugs may require different conversion factors or should only be dosed by weight or BSA specifically.

Q5: Should I use this for all medication conversions?
A: No, only use when specifically directed by drug protocols or clinical guidelines.